A selection of videos from the International Year of Crystallography playlist on YouTube


[Electron density map, protein model and crystal]

Diving into the heart of the molecules of life

Taking atomic snapshots is very important to biologists who want to understand the architecture of the macromolecules that make up our cells. However, these nano-objects are far too small to be observed with a microscope. This is why other methods such as X-ray crystallography are needed to provide accurate images at an atomic scale. This film, Diving into the heart of the molecules of life, follows the different steps of a crystallographic study and describes the work of researchers at CNRS (ARN Laboratory, Institut de Biologie Moléculaire et Cellulaire, Strasbourg), from the purification of a macromolecule from living cells, its crystallisation and the analysis of the crystals using synchrotron radiation, to the assembly of a three-dimensional image. This movie covers several aspects of scientists' work which are not widely known: the cloning of biomolecules, the use of large instruments such as synchrotron X-ray sources, and 3D visualisation.

Category: Education. Duration: 13m 26s

cc_by-nc-sa License: Creative Commons